Entry 1 sense Webster, 1913 Abnegation /ăb.nĭgāʹshən/ · Ab·ne·ga·tion · IPA /ˌæbnəˈɡeɪ̯ʃən/ 01 n. a denial; a renunciation. 1. a denial; a renunciation. “With abnegation of God, of his honor, and of religion, they may retain the friendship of the court.” — Knox.