Entry 2 senses · 2 variants Webster, 1913 Afro-American · IPA n. adj. 01 n. an American whose ancestors were born in Africa. 1. an American whose ancestors were born in Africa. Syn. African-American, African. 02 adj. of or pertaining to or characteristic of Americans of African ancestry or their history or culture. 1. of or pertaining to or characteristic of Americans of African ancestry or their history or culture. Syn. African-American.