Entry 1 sense Webster, 1913 Altruistic /ôlˌ-tro͞o-ĭs'-tĭk/ · Al·tru·is·tic · IPA /ˌæl.tɹuˈɪs.tɪk/ 01 a. Regardful of others; beneficent; unselfish; -- opposed to egoistic or selfish. 1. Regardful of others; beneficent; unselfish; -- opposed to egoistic or selfish.