Entry 2 senses · 2 variants Webster, 1913 biochemical · bi·o·chem·ic·al · IPA /ˌbaɪəʊˈkɛmɪkəl/ adj. n. 01 adj. of or pertaining to biochemistry. 1. of or pertaining to biochemistry. 02 n. a chemical substance produced by a living organism, or such a substance produced synthetically. 1. a chemical substance produced by a living organism, or such a substance produced synthetically.