Entry 1 sense Webster, 1913 Dysphoria /dĭs-fôr′-ē-ə/ · Dys·pho·ri·a · IPA /dɪsˈfɔːɹi.ə/ 01 n. Impatience under affliction; morbid restlessness; dissatisfaction; the fidgets. 1. Impatience under affliction; morbid restlessness; dissatisfaction; the fidgets.(Med.)