Entry 2 senses · 2 variants Webster, 1913 Eradicative · E·rad·i·ca·tive · IPA a. n. 01 a. Tending or serving to eradicate; curing or destroying thoroughly, as a disease or any evil. 1. Tending or serving to eradicate; curing or destroying thoroughly, as a disease or any evil. 02 n. A medicine that effects a radical cure. 1. A medicine that effects a radical cure.(Med.)