Entry 1 sense Webster, 1913 homophobia /hōmˌ-əf-ōb'-ē-ə/ · hom·o·pho·bi·a · IPA /ˌhoʊ.məˈfoʊ.bi.ə/ 01 n. A strong dislike or fear of homosexuals, especially to an unreasonable degree. 1. A strong dislike or fear of homosexuals, especially to an unreasonable degree.