Entry 2 senses Webster, 1913 Irresponsibly · Ir·re·spon·si·bly · IPA /ˌɪ.ɹɪˈspɑːn.sə.bli/ 01 adv. So as not to be responsible. 1. So as not to be responsible. 2. In an irresponsible{2} manner; without due care or diligence.