Entry 1 sense Webster, 1913 Karyostenotic · Kar·y·o·ste·not·ic · IPA 01 a. Pertaining to, or connected with, karyostenosis; as, the karyostenotic mode of nuclear division. 1. Pertaining to, or connected with, karyostenosis; as, the karyostenotic mode of nuclear division.(Biol.)