Entry 2 senses · 2 variants Webster, 1913 Maculate · Mac·u·late · IPA /ˈmækjʊleɪt/ v. t. a. 01 v. t. To spot; to stain; to blur. 1. To spot; to stain; to blur. “Maculate the honor of their people.” — Sir T. Elyot. 02 a. Marked with spots or maculae; blotched; hence, defiled; impure; as, most maculate thoughts. 1. Marked with spots or maculae; blotched; hence, defiled; impure; as, most maculate thoughts.