Entry 1 sense Webster, 1913 Shopkeeper /shäp'-kēpˌ-ẽr/ · Shop·keep·er · IPA /ˈʃɒpkiːpɚ/ 01 n. A trader who sells goods in a shop, or by retail; -- in distinction from one who sells by wholesale. 1. A trader who sells goods in a shop, or by retail; -- in distinction from one who sells by wholesale.