Entry 1 sense Webster, 1913 Simplification /sĭmˌ-pləf-ĭk-āsh'-ən/ · Sim·pli·fi·ca·tion · IPA /ˌsɪm.plə.fəˈkeɪ.ʃən/ 01 n. The act of simplifying. 1. The act of simplifying.