Entry 1 sense Webster, 1913 Star-crossed /(stär"krŏst` ; 115)/ · Star·-crossed · IPA /ˈstɑɹˌkɹɔst/ 01 a. Not favored by the stars; ill-fated. 1. Not favored by the stars; ill-fated.[Poetic] “Such is my star-crossed destiny.” — Massinger.