Entry 2 senses · 2 variants Webster, 1913 Metabola · Me·tab·o·la · IPA n. n. pl. 01 n. A change or mutation; a change of disease, symptoms, or treatment. 1. A change or mutation; a change of disease, symptoms, or treatment.(Med.) 02 n. pl. A comprehensive group of insects, including those that undegro a metamorphosis. 1. A comprehensive group of insects, including those that undegro a metamorphosis.(Zool.)